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The DSM-outlines the following criterion to make a diagnosis of depression. A prominent and persistent period of depressed mood or markedly diminished interest or pleasure in all, or almost all, activities that predominates in the clinical picture. The individual must be experiencing five or more symptoms during the same 2-week period and at least one of the symptoms should be either (1) depressed mood or (2) loss of interest or pleasure. Depression Definition and DSM-Diagnostic Criteria Depression DSM-Diagnostic Criteria.

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