What is her2 negative

Treatments for HER2-Negative Advanced Breast Cancer HER2-negative breast cancer means your tumor cells dont have a specific protein on their surfaces called HER2. HERFISH Testing in Breast Cancer: What You Should Know. If breast cancer cells dont have abnormal levels of HERproteins, then the breast cancer is considered HER2-negative. There are several tests used to find out if breast cancer is HER2-positive.

Most patients with metastatic breast cancer have HER2-negative breast cancer. Normally present in breast tissue, HERreceptors help control how breast cells grow and divide. If your cancer is HER2-negative, it may still be estrogen- or progesterone-positive.

These cancers tend to grow and spread faster than other breast cancers, but are much more likely to respond to treatment with drugs that target the HERprotein. Cancer cells that are HERnegative may grow more slowly and are less likely to recur (come back) or spread to other parts of the body than cancer cells that have a large amount of HERon their surface. When a breast cancer is HER2-negative, it means that the cancerous cells do not contain high levels of the protein HER2.

HER2-positive breast cancers are often more aggressive than HER2-negative breast cancers. Breast cancer cells with higher than normal levels of HERare called HER2-positive. Your doctor will talk with you about the plan thats best for you. Thats important because drugs that fight cancer by targeting this protein wont work for you.

Breast Cancer HERStatus HERPositive Breast Cancer HERis a growth-promoting protein on the outside of all breast cells. HER2-Positive Breast Cancer In about of breast cancers, the cells make too much of a protein known as HER2.

Definition of HERnegative - NCI Dictionary of Cancer

M HER2-negative breast cancer means tests show no abnormality in the human epidermal growth factor receptor gene. Checking for the amount of HERon some types of cancer cells may help plan treatment. If HER2-negative breast cancer is also hormone receptor positive, the most common treatment is hormonal therapy, but chemotherapy or targeted therapy may also be given. HERStatus: Tests, Treatments, and More Jan 2 20HER2-positive breast cancers tend to grow faster and are more likely to spread and come back compared to HER2-negative breast cancers.

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