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Other popular SSRIS include citalopram ( Celexa fluoxetine ( Prozac and sertraline). Zoloft and Lexapro came in first for a combination of effectiveness and fewer side effects, followed by Prozac (fluoxetine Paxil (paroxetine Cymbalta, and Luvox among others). Jan 2 20By looking at 1studies of the most popular antidepressants, researchers ranked the top drugs in the journal The Lancet. Top Rated Antidepressants of 20- Consumer Health Digest Jan 0 20Paxil is a type of antidepressant known as an SSRI (selective serotonin reuptake inhibitor which is thought to boost mood by making more of the neurotransmitter serotonin available in the brain.

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